| Event | Date | Location | |
| Spring Training: Atlanta Braves vs Pittsburgh Pirates | Thu. Mar 4, 2010 1:05PM | Lake Buena Vista, FL - Champion Stadium |  |
Spring Training: Pittsburgh Pirates vs
Philadelphia Phillies | Sat. Mar 6, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Pittsburgh Pirates vs Minnesota Twins | Sun. Mar 7, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Tampa Bay Rays vs Pittsburgh Pirates | Mon. Mar 8, 2010 1:05PM | Port Charlotte, FL - Charlotte County Stadium | |
| Spring Training: Pittsburgh Pirates vs New York Yankees | Mon. Mar 8, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Pittsburgh Pirates vs Baltimore Orioles | Wed. Mar 10, 2010 7:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Pittsburgh Pirates vs Tampa Bay Rays | Thu. Mar 11, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Atlanta Braves vs Pittsburgh Pirates | Fri. Mar 12, 2010 1:05PM | Lake Buena Vista, FL - Champion Stadium | |
| Spring Training: Pittsburgh Pirates vs New York Yankees | Sun. Mar 14, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
Spring Training: Pittsburgh Pirates vs
Philadelphia Phillies | Mon. Mar 15, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Pittsburgh Pirates vs Detroit Tigers | Wed. Mar 17, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Pittsburgh Pirates vs Boston Red Sox | Fri. Mar 19, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Pittsburgh Pirates vs Tampa Bay Rays | Sun. Mar 21, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Pittsburgh Pirates vs Houston Astros | Tue. Mar 23, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Pittsburgh Pirates vs Boston Red Sox | Wed. Mar 24, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Pittsburgh Pirates vs Atlanta Braves | Thu. Mar 25, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Houston Astros vs Pittsburgh Pirates | Fri. Mar 26, 2010 1:05PM | Kissimmee, FL - Osceola County Stadium | |
| Spring Training: Pittsburgh Pirates vs Toronto Blue Jays | Sat. Mar 27, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
| Spring Training: Tampa Bay Rays vs Pittsburgh Pirates | Sun. Mar 28, 2010 1:05PM | Port Charlotte, FL - Charlotte County Stadium | |
Spring Training: Philadelphia Phillies vs
Pittsburgh Pirates | Sun. Mar 28, 2010 1:05PM | Clearwater, FL - Bright House Networks Field | |
| Spring Training: Pittsburgh Pirates vs Houston Astros | Mon. Mar 29, 2010 1:05PM | Bradenton, FL - Mckechnie Field | |
Spring Training: Philadelphia Phillies vs
Pittsburgh Pirates | Thu. Apr 1, 2010 1:05PM | Clearwater, FL - Bright House Networks Field | |
| MLB Exhibition: Philadelphia Phillies vs Pittsburgh Pirates | Fri. Apr 2, 2010 7:05PM | Philadelphia, PA - Citizens Bank Park | |
| MLB Exhibition: Philadelphia Phillies vs Pittsburgh Pirates | Sat. Apr 3, 2010 1:05PM | Philadelphia, PA - Citizens Bank Park | |
| Pittsburgh Pirates vs Los Angeles Dodgers | Mon. Apr 5, 2010 1:35PM | Pittsburgh, PA - PNC Park | |
| Pittsburgh Pirates vs Los Angeles Dodgers | Wed. Apr 7, 2010 7:05PM | Pittsburgh, PA - PNC Park | |
| Pittsburgh Pirates vs Los Angeles Dodgers | Thu. Apr 8, 2010 12:35PM | Pittsburgh, PA - PNC Park | |
| Arizona Diamondbacks vs Pittsburgh Pirates | Fri. Apr 9, 2010 6:40PM | Phoenix, AZ - Chase Field (formerly Bank One Ballpark) | |
| Arizona Diamondbacks vs Pittsburgh Pirates | Sat. Apr 10, 2010 5:10PM | Phoenix, AZ - Chase Field (formerly Bank One Ballpark) | |
| Arizona Diamondbacks vs Pittsburgh Pirates | Sun. Apr 11, 2010 1:10PM | Phoenix, AZ - Chase Field (formerly Bank One Ballpark) | |
