| Event | Date | Location | |
| Pittsburgh Panthers vs Youngstown State Penguins | Sat. Nov 28, 2009 12:00PM | Pittsburgh, PA - Petersen Events Center |  |
| Duquesne Dukes vs Pittsburgh Panthers | Wed. Dec 2, 2009 7:00PM | Pittsburgh, PA - Mellon Arena | |
| Pittsburgh Panthers vs New Hampshire Wildcats | Fri. Dec 4, 2009 7:00PM | Pittsburgh, PA - Petersen Events Center | |
Jimmy V Classic: Butler vs
Georgetown AND Indiana vs
Pittsburgh | Tue. Dec 8, 2009 7:00PM | New York, NY - Madison Square Garden | |
| Pittsburgh Panthers vs Kent State Golden Flashes | Sat. Dec 12, 2009 12:00PM | Pittsburgh, PA - Petersen Events Center | |
| Pittsburgh Panthers vs Mount St. Marys Mountaineers | Sat. Dec 19, 2009 4:00PM | Pittsburgh, PA - Petersen Events Center | |
| Pittsburgh Panthers vs Ohio Bobcats | Tue. Dec 22, 2009 7:00PM | Pittsburgh, PA - Petersen Events Center | |
| Pittsburgh Panthers vs Depaul Blue Demons | Mon. Dec 28, 2009 7:00PM | Pittsburgh, PA - Petersen Events Center | |
| Syracuse Orange vs Pittsburgh Panthers | Sat. Jan 2, 2010 12:00PM | Syracuse, NY - Carrier Dome | |
| Cincinnati Bearcats vs Pittsburgh Panthers | Mon. Jan 4, 2010 7:00PM | Cincinnati, OH - Fifth Third Arena | |
| UConn Huskies vs Pittsburgh Panthers | Wed. Jan 13, 2010 7:00PM | Hartford, CT - XL Center - (Formerly Hartford Civic Center) | |
| Pittsburgh Panthers vs Louisville Cardinals | Sat. Jan 16, 2010 12:00PM | Pittsburgh, PA - Petersen Events Center | |
| Pittsburgh Panthers vs Georgetown Hoyas | Wed. Jan 20, 2010 7:00PM | Pittsburgh, PA - Petersen Events Center | |
| Seton Hall Pirates vs Pittsburgh Panthers | Sun. Jan 24, 2010 2:00PM | Newark, NJ - Prudential Center | |
| Pittsburgh Panthers vs St. Johns Red Storm | Thu. Jan 28, 2010 7:00PM | Pittsburgh, PA - Petersen Events Center | |
| West Virginia Mountaineers vs Pittsburgh Panthers | Wed. Feb 3, 2010 7:00PM | Morgantown, WV - West Virginia University Coliseum | |
| Pittsburgh Panthers vs Seton Hall Pirates | Sat. Feb 6, 2010 6:00PM | Pittsburgh, PA - Petersen Events Center | |
| Pittsburgh Panthers vs Robert Morris Colonials | Mon. Feb 8, 2010 8:00PM | Pittsburgh, PA - Petersen Events Center | |
| Pittsburgh Panthers vs West Virginia Mountaineers | Fri. Feb 12, 2010 9:00PM | Pittsburgh, PA - Petersen Events Center | |
| Marquette Golden Eagles vs Pittsburgh Panthers | Thu. Feb 18, 2010 8:00PM | Milwaukee, WI - Bradley Center | |
| Pittsburgh Panthers vs Villanova Wildcats | Sun. Feb 21, 2010 12:00PM | Pittsburgh, PA - Petersen Events Center | |
| Notre Dame Fighting Irish vs Pittsburgh Panthers | Wed. Feb 24, 2010 7:00PM | Notre Dame, IN - Joyce Center | |
| St. Johns Red Storm vs Pittsburgh Panthers | Sat. Feb 27, 2010 12:00PM | New York, NY - Madison Square Garden | |
| Pittsburgh Panthers vs Providence Friars | Thu. Mar 4, 2010 9:00PM | Pittsburgh, PA - Petersen Events Center | |
| Pittsburgh Panthers vs Rutgers Scarlet Knights | Sat. Mar 6, 2010 4:30PM | Pittsburgh, PA - Petersen Events Center | |
